“mRNA vaccines — a new era in vaccinology | Nature Reviews Drug Discovery” https://www.nature.com/articles/nrd.2017.243
People have been messing around with mRNA vaccines for 30 years:
«The first report of the successful use of in vitro transcribed (IVT) mRNA in animals was published in 1990, when reporter gene mRNAs were injected into mice and protein production was detected5.»